protocol deviations造句

The letter said the enrollment of ineligible subjects, such as the cancer patient, " can be a serious protocol deviation ."
:: : Circling back to my original intent : if we could assume there is a good, comprehensive article ( or section ) on the management of clinical trials, including the management of feasibility studies, documentation approval, monitoring, subject progress, protocol deviations, etc ., one could say we don't really need a separate article on CTMS, which would be just " the software that does that ".
It's difficult to find protocol deviations in a sentence. 用protocol deviations造句挺难的